Product Description
Raw Avanafil Powder Basic Characters
| Name: | Avanafil powder |
| CAS: | 330784-47-9 |
| Molecular Formula: | C23H26ClN7O3 |
| Molecular Weight: | 483.95 |
| Melt Point: | 150-152°C |
| Storage Temp: | RT |
| Color: | White powder |
What is Avanafil Powder?
Avanafil powder is the powder form of the ED drug Avanafil, it is used to treat men who have erectile dysfunction (also called sexual impotence). Avanafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works.
Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body’s normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, avanafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, avanafil will not work to cause an erection.
There are the different forms of Avanafil including powder form, tablet, and capsule. etc. Avanafil powder is the base ingredient used to make oral Avanafil tablets or pills. Avanafil’s brand name is Stendra, it has 50mg, 100mg, and 200mg.
How does Avanafil powder work?
Raw Avanafil powder for sale in the market, inhibits the cGMP-specific phosphodiesterase type 5 (PDE5) which is responsible for the degradation of cGMP in the corpus cavernosum located around the penis. Sexual arousal results in the local release of nitric oxide, which in turn stimulates the enzyme guanylate cyclase to produce cGMP. Elevated levels of cGMP result in local smooth muscle relaxation and increased blood flow to the penis (i.e. an erection).
As PDE5 inhibitors like avanafil require the endogenous release of nitric oxide in order to exert their pharmacologic effect, they have no effect on the user in the absence of sexual stimulation/arousal.
What is Avanafil powder use for?
Avanafil powder for sale is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, avanafil works by increasing blood flow to the penis to help a man get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, and syphilis). To decrease your risk of infection, always use an effective barrier method (latex or polyurethane condom/dental dams) during all sexual activity.
How to use Avanafil Pills?
Avanafil is available in different forms, like pure powder form, tablet and pill form. The avanafil powder is the base ingredient to make avanafil tablets or pills, they have dosage range from 50mg-100mg-200mg. The brand name of Avanafil tablet and pill is Stendra.
Read the Patient Information Leaflet if available from your pharmacist before you start taking avanafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take an avanafil tablet or pill by mouth with or without food as directed by your doctor, usually as needed. This medication is available in different doses. Depending on your dose, take your avanafil dosage about 15 minutes or 30 minutes before sexual activity. Follow your doctor’s instructions carefully on how many minutes before sexual activity you should take this medication. Do not take more than once daily.
The avanafil dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Avanafil Vs Tadalafil: What is the difference? Which one is better for you?
In general, while both medications can and occasionally do cause side effects, Avanafil (Stendra) is less likely to cause common side effects and has fewer severe side effects than older ED treatment medications, such as Viagra (sildenafil), Cialis (tadalafil) and Levitra (vardenafil). When Avanafil Vs Tadalafil, what is the difference? Which one is better for you to use? Let’s see the details as below:
| Items | Avanafil (Stendra) | Tadalafil (Cialis) |
| Definition | Stendra (avanafil) is an effective option for erectile dysfunction taken 30 minutes before sexual activity. It’s available only as a brand name medication right now, so it can be a little more expensive than other options. | Cialis (tadalafil) is the only medication in its class that treats both erectile dysfunction and enlarged prostate symptoms. You can also take it on a regular basis, which can allow for more spontaneity. |
| Indications | Erectile dysfunction | Erectile dysfunction Enlarged prostate (BPH) |
| Pros and Cons | Pros •Works faster than other medications in its class (can be taken 15 minutes before sex) •Doesn’t have to be taken everyday to work •Can be taken with or without food •Well tolerated
Cons •Can’t be used if you’ve recently taken nitrates like Isordil, Imdur, or nitroglycerin (Nitro-BID, Nitro-Dur, Nitrostat) •Only available as a brand name medication, so it can be expensive •Not recommended for people who’ve had a heart attack or stroke in the past 6 months | Pros •A first-choice medication for treating erectile dysfunction •Can be taken either as needed, or on a regular basis for those who need it more regularly — this means you can be more spontaneous about the timing of sex. •Lasts longer than Viagra (sildenafil)
Cons •Can’t be taken if you’ve had a heart attack in the past 3 months, or a stroke or heart failure in the past 6 months •Can’t be used if you’ve recently taken nitrates like Isordil, Imdur, or nitroglycerin (Nitro-BID, Nitro-Dur, Nitrostat) •Could have more side effects for people who are 65 or older — use this medication with care |
| Common Side Effects | •Headache (7%) •Flushing (4%) •Stuffy nose (3%) •Flu-like symptoms (3%) •Back pain (2%) | •Headache (11-15%) •Indigestion (4-10%) •Back pain (3-6%) |
| Warnings | •RISK OF HEART ATTACK OR STROKE •INCREASED SIDE EFFECTS WITH OTHER MEDICATIONS •PROLONGED ERECTION •VISION LOSS •HEARING LOSS •LOW BLOOD PRESSURE | •Risk of heart attack or stroke •Low blood pressure •Prolonged erection •Vision changes •Hearing loss •Interactions with other medications |
| Prices | Stendra 6 tablets / 200mg US$420.78 | Tadalafil (cialis) 30 tablets / 5mg US$25.94 |
Avanafil Vs Sildenafil: Which one is stronger?
The brand name of Avanafil powder is Stendra, and the brand name of Sildenafil citrate is Viagra. they all both medications used to treat ED. Avanafil Vs Sildenafil, which one is stronger? Let’s see the frequently asked questions about Avanafil and Sildenafil:
① Is Avanafil work faster than Sildenafil?
Yes, one of the biggest advantages of Avanafil is that it works quickly, often in as little as 15 minutes after consumption. Viagra and generic medications containing sildenafil, on the other hand, typically take action in about one hour. This means that you’ll need to take the medication slightly earlier than Avanafil (Stendra) for it to be effective by the time you plan to have sex.
② Is Avanafil last longer than Sildenafil?
Yes, Avanafil has a slightly longer half-life than Sildenafil, meaning one tablet of it will generally provide relief from erectile dysfunction for longer than an equivalent dose of Sildenafil.
How long does Avanafil last? Avanafil powder, the active ingredient in Stendra, has a terminal half-life of around five hours, meaning it takes five hours to reach 50 percent of its original concentration in your body.
Sildenafil, the active ingredient in Viagra, has a half-life of four hours.
Cialis(tadalafil) is a long-lasting medication for ED. In fact, it’s often referred to as the “weekend pill” due to its 17.5-hour half-life, which allows a single dose to provide relief from erectile dysfunction for as long as 36 hours.
③ Does Avanafil is better than Sildenafil for ED treatment?
Clinical studies of avanafil (the active ingredient in Stendra) and sildenafil (the active ingredient in Viagra) show that both medications are very effective at treating erectile dysfunction for most men.
④ Avanafil has fewer side effects than Sildenafil?
Yes, both Avanafil and Sildenafil have the potential to cause drug interactions when they’re taken with other medications and substances. Avanafil and Sildenafil can both cause similar side effects. However, study data show that fewer men experience several common side effects, such as headaches and nasal congestion, with Avanafil than with Sildenafil.
⑤ Avanafil is safer than Sildenafil?
Avanafil and Sildenafil are both safe medications, provided they’re used as prescribed. If you’re a healthy male with no history of cardiovascular disease, kidney disease, high blood pressure, or other health issues, you can safely use either drug as prescribed by your doctor.
⑥ Avanafil is cheaper than Sildenafil?
No. Because the active ingredient in Viagra Sildenafil powder is now available as a generic medication (sildenafil), it’s a significantly more affordable option than Avanafil. From a value-for-money perspective, generic sildenafil is the most affordable option for treating erectile dysfunction. It contains the exact same active ingredient as Viagra and works the same way within your body, making it a comparatively cost-effective ED treatment option.
So Avanafil Vs Sildenafil in summary:
-Stendra and Viagra are both medications for treating erectile dysfunction. Both belong to a class of medications called PDE5 inhibitors, which work by increasing blood flow to the erectile tissue inside your penis.
-Both medications can be taken before sex. Viagra typically starts working in 30 minutes to one hour, whereas Stendra is a faster-acting medication that can begin working in 15 to 30 minutes.
-Although both medications work by increasing blood flow to your penis, Stendra is more selective in its effects. This means that it’s slightly less likely to cause some side effects than Viagra.
-Contrary to popular belief, neither Stendra nor Viagra causes random erections or affects your sex drive. Both medications only cause erections when you have a form of sexual stimulation, such as sexual activity or a sexual thought.
-As an older medication, Viagra is now available as a generic, making it more affordable than Stendra. The generic name for Viagra is sildenafil. Because Stendra is so new, it’s unlikely that a generic version will be made available in the next few years.
What other famous ED treatment drug besides Avanafil powder?
Tadalafil Powder: Tadalafil powder is the active ingredient of Cialis, it is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly.
Tadalafil can last longer than both Avanafil and Sildenafil and has fewer side effects. Cialis tablet or pill has different dosages from 5mg,10mg, and 20mg.
Vardenafil Hydrochloride Powder: Vardenafil HCL is used to treat men with erectile dysfunction (sexual impotence). It belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. After the penis is stroked, vardenafil maintains an erection by increasing blood flow. Without physical activity, such as that occurring during sexual intercourse, vardenafil will not cause an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, and syphilis).
Frequently asked questions about Avanafil Powder
① How often can I take Avanafil?
You should not take Stendra (avanafil) more than once in a 24-hour period.
② How long does it take for Avanafil to work?
It’s recommended to take Stendra (avanafil) about 15-30 minutes before sexual activity to give the medication time to kick in. For some people, it can work faster, within 15 minutes, and for others might take longer.
③ Do I need a prescription for Avanafil?
Yes, Stendra (avanafil) is a prescription-only medication. A lot of insurance companies don’t cover medications used for erectile dysfunction so you might be paying a cash price. But you can buy Avanafil powder with or without a prescription, Avanafil powder for sale is the active ingredient of the Stendra tablet or pill.
④ Should you take Avanafil if you do not need it?
No. If you haven’t been told that you have erectile dysfunction by a healthcare provider, you shouldn’t take this for sexual performance without first discussing it with your provider.
Where to buy pure Avanafil Powder?
Avanafil powder for sale is the active ingredient of Stendra tablets or pills. Avanafil is a relatively new ED medication, Avanafil was developed throughout the 2000s and approved in April 2012 by the FDA. Avanafil is an erectile dysfunction medication. It’s part of a class of medications referred to as PDE5 inhibitors, which work by increasing blood flow to the erectile tissue located inside your penis. By improving blood flow to your penis, Stendra makes it easier to get and maintain an erection when you feel sexually aroused.
If it is expensive for you to buy an Avanafil tablet form Stendra, it is much more affordable to buy Avanafil powder from the an Avanafil powder manufacturer or factory directly, as Avanafil pure powder is the active ingredient of the brand Stendra. AASraw is a professional manufacturer of Avanafil powder, has an independent lab and large factory as support, all production will be carried out under CGMP regulation and a trackable quality control system. The supply system is stable, and both retail and wholesale orders are acceptable. AASraw can provide pure Avanafil powder from gram to kilogram, you can buy Avanafil powder here with or without a prescription, easy and affordable price.
Raw Avanafil Powder Testing Report-HNMR
What is HNMR and What does HNMR spectrum tell you? H Nuclear Magnetic Resonance (NMR) spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion.
Avanafil powder(330784-47-9)-COA
Avanafil powder(330784-47-9)-COA
How to buy Avanafil Powder from AASraw?
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❷To provide us with your inquired quantity and address.
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Author of this article:
Dr. Monique Hong graduated from UK Imperial College London Faculty of Medicine
Scientific Journal paper Author:
1. O.A. El-Kawy
Egyptian Atomic Energy Authority, 13759, Cairo, Egypt
2. Jun Kotera
Advanced Medical Research Laboratories, Mitsubishi Tanabe Pharma Corp., Yokohama, Japan
3. Elif Öztürk Er
Yıldız Technical University, Chemical Engineering Department, 34349 İstanbul, Turkey
4. Jinah Jung MD
Department of Clinical Pharmacology and Therapeutics, University of Ulsan, Asan Medical Center, Seoul, Korea
5. Run Wang MD
University of Texas Medical School at Houston and MD Anderson Cancer Center, Houston, TX, USA
In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. Aasraw has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge and commend the exhaustive research and development work done by the scientists working on this substance.
Reference
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[2].“Mesterolone and idiopathic male infertility: a double-blind study. World Health Organization Task Force on the Diagnosis and Treatment of Infertility.” Int J Androl. 1989 Aug;12(4):254-64. PMID: 2680994
[3]. “Mesterolone: a new androgen.”Drug Ther Bull. 1972 Jul 21;10(15):58-9. PMID: 5073836
[4].Ho EN, Leung DK, Leung GN, Wan TS, Wong HN, Xu X, Yeung JH. “Metabolic studies of mesterolone in horses.” Anal Chim Acta. 2007 Jul 16;596(1):149-55. doi: 10.1016/j.aca.2007.05.052. Epub 2007 Jun 3.PMID: 17616252
[5].Allouh MZ, Aldirawi MH. “Influence of mesterolone on satellite cell distribution and fiber morphology within maturing chicken pectoralis muscle.” Anat Rec (Hoboken). 2012 May;295(5):792-9. doi: 10.1002/ar.22439. Epub 2012 Mar 15. PMID: 22419647.
[6].Häfliger O, Hauser GA.[Therapeutic trials of Proviron in frigidity]. Ther Umsch. 1973 Jul;30(7):533-6. PMID: 4578455
[7]. Luisi M, Franchi F. “Double-blind group comparative study of testosterone undecanoate and mesterolone in hypogonadal male patients.” J Endocrinol Invest. 1980 Jul-Sep;3(3):305-8. doi: 10.1007/BF03348281. PMID: 7000879
