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Lorcaserin HCL powder

Rating: SKU: 1431697-94-7. Category:

Other names:Lorcaserin HCL,Belviq

AASraw is the professional manufacturer of Lorcaserin hydrochloride raw powder which has independent lab and large factory as support, all production will be carried out under CGMP regulation and trackable quality control system. The supply system is stable, both retail and wholesale orders are acceptable.Welcome to order from AASraw!

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Product Description

Lorcaserin hydrochloride Powder Video-AASraw

 


Raw Lorcaserin hydrochloride Powder Basic Characters

Name:Lorcaserin hydrochloride powder
CAS:1431697-94-7
Molecular Formula:C11H15Cl2N
Molecular Weight:232.1525
Melt Point: 212°C
Storage Temp:-20℃
Color: White powder

 


What is Lorcaserin hydrochloride Powder?

Lorcaserin hydrochloride is a hydrochloride obtained by the reaction of lorcaserin with one equivalent of hydrochloric acid. Used as an anti-obesity drug. It has a role as a serotonergic agonist and an appetite depressant.

Lorcaserin hydrochloride powder affects chemical signals in the brain that control appetite. Lorcaserin HCL powder works by helping you feel full with smaller meals. Lorcaserin hydrochloride powder is used together with diet and exercise to treat obesity. Lorcaserin hydrochloride powder is sometimes used to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure.

What is Lorcaserin hydrochloride good for?

Lorcaserin hydrochloride is used to help adults who are obese or who are overweight and have weight-related medical problems to lose weight and keep from gaining back that weight. Lorcaserin must be used along with a reduced-calorie diet and an exercise plan. Lorcaserin is in a class of medications called serotonin receptor agonists. It works by increasing feelings of fullness so that less food is eaten.

Lorcaserin hydrochloride is used together with a reduced-calorie diet and proper exercise to help you lose weight. It is also used in overweight people who may also have diabetes, high blood pressure, high cholesterol, or heart disease.

The benefits of Lorcaserin hydrochloride

Lorcaserin hydrochloride is an orally administered medication that promotes weight loss. It is used with diet and exercise in overweight adults with a weight-related medical problem or obese adults to lose weight and keep it off.

Lorcaserin hydrochloride is a serotonin 2C (5-HT2C) receptor agonist. lorcaserin is thought to selectively stimulate 5-HT2C receptors in the hypothalamus, the area of the brain known to play a major role in regulating hunger and food intake. By activating these receptors, lorcaserin may decrease food consumption by decreasing appetite and making a person feel full even after eating less food than usual.

Lorcaserin hydrochloride is a serotonin 2C receptor agonist indicated for the treatment of chronic weight management in adults with a body mass index (BMI) of 30 or greater (obese) as an addition to a reduced-calorie diet and exercise. lorcaserin is also approved for use by adults with a BMI of 27 or greater (overweight) and who have at least one weight-related condition such as high blood pressure (hypertension), type 2 diabetes, or high cholesterol (dyslipidemia).

Lorcaserin hydrochloride used as an anti-obesity drug

Obesity is a major health priority necessitating safe and effective strategies to address the obesity epidemic. Lorcaserin is a serotonergic agonist specific to the 5HT- 2C receptor approved for chronic management of obesity in patients with a BMI ≥ 30 kg/m(2) or a BMI ≥ 27 kg/m(2) with comorbidities related to obesity.

Lorcaserin is a unique highly selective serotonergic agonist designed to mitigate the risks associated with previous agents in this class. At therapeutic doses, it is well tolerated and produces modest but clinically meaningful weight loss with significant improvement in cardiometabolic parameters. Therapeutic efficacy should be assessed at 12 weeks (≥ 5% weight loss) to identify responders who will derive maximum weight loss and metabolic benefit from long-term therapy. The results of the ongoing cardiovascular outcomes trial (CAMELLIA TIMI 61) will determine the role of lorcaserin in the primary prevention of diabetes in overweight/obese individuals and its use in the high-risk population of patients with established cardiovascular disease or multiple cardiovascular risk factors.

Where to buy Lorcaserin hydrochloride Powder?

Lorcaserin is used to help adults who are obese or who are overweight and have weight-related medical problems to lose weight and keep from gaining back that weight. Lorcaserin must be used along with a reduced-calorie diet and an exercise plan. Lorcaserin is in a class of medications called serotonin receptor agonists. It works by increasing feelings of fullness so that less food is eaten.

Raw Lorcaserin hydrochloride Powder Testing Report-HNMR

Lorcaserin hydrochloride HNMR

What is HNMR and What does HNMR spectrum tell you? 
H Nuclear Magnetic Resonance (INMR)spectroscopy is an analytical chemistry technique used in quality control
and research for determining the content and purity of a sample as well as its molecular structure. For 
example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR 
can(either be used to match against spectral libraries or to infer the basic structure directly. Once the
basic structure is known, NMR can be used to determine molecular conformation in solution as well as 
studying physical properties at the molecular level such as conformational exchange, phase changes,
solubility, and diffusion.

Lorcaserin hydrochloride(1431697-94-7)-COA

Lorcaserin hydrochloride(1431697-94-7)-COA

How to buy Lorcaserin hydrochloride Powder from AASraw?

❶To contact us by our email inquiry system, or leave your WhatsApp number to us, our customer service representative(CSR) will contact you in 12 hours.

❷To provide us with your inquired quantity and address.

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Author of this article:
Dr. Monique Hong graduated from UK Imperial College London Faculty of Medicine

Scientific Journal paper Author:
1. Stefan Wagner
The Rowett Institute, University of Aberdeen, Aberdeen, UK
Stefan Wagner and Daniel I. Brierley contributed equally to this work.
2. Qihua Zhu
Jiangsu Key Laboratory of Drug Design and Optimization
Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210009, China
3. Thiago F. Ribeiro
Instituto de Química, Universidade Federal de Goiás, Campus Samambaia, PO Box 131, Goiânia, GO 74690-900, Brazil
4. Dattatraya V. Wani
Department of Pharmaceutical Chemistry, Maulana Azad Education Trust’s Y.B. Chavan College of Pharmacy, Aurangabad, Maharashtra, India
In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. Aasraw has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge and commend the exhaustive research and development work done by the scientists working on this substance.

Reference

[1] Belviq (lorcaserin hydrochloride) tablet [Eisai, Inc]”. DailyMed. Eisai, Inc. August 2012. Archived from the original on 21 October 2013. Retrieved 21 October 2013.

[2] “FDA requests the withdrawal of the weight-loss drug Belviq, Belviq XR (lorcaserin) from the market”. U.S. Food and Drug Administration (FDA). 14 January 2020. Retrieved 1 April 2020.

[3] “FDA In Brief: FDA Requests Voluntary Withdrawal of Weight-Loss Medication After Clinical Trial Shows an Increased Occurrence of Cancer”. FDA. 13 February 2020.

[4] “Belviq XR (lorcaserin hydrochloride) extended-release tablets”. U.S. Food and Drug Administration (FDA). 26 October 2016. Retrieved 14 January 2020.

[5] “Drug Approval Package: Belviq (lorcaserin hydrochloride) Tablets NDA #022529”. U.S. Food and Drug Administration (FDA). 7 August 2012. Retrieved 14 January 2020.


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