Women’s Viagra? A Comprehensive Guide to Flibanserin Powder, the Sexual Enhancement Solution
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Flibanserin raw powder video
Flibanserin basic Characters
| Name: | Flibanserin |
| CAS: | 167933-07-5 |
| Molecular Formula: | C20H21F3N4O |
| Molecular Weight: | 390.4 |
| Melt Point: | 225°C |
| Storage Temp: | RT |
| Color: | White crystalline powder |
Flibanserin powder overview
Flibanserin powder,the raw material of drug Flibanserin,usually made into Flibanserin tablets/pills,is a female sex enhancing drug,which used to enhance sexual desire and decrease emotional distress in premenopausal women with hypoactive sexual desire disorder (HSDD).Although flibanserin has been called “the female Viagra”, the way in which it works is distinctly different from Viagra. Viagra works by increasing blood flow to the genitals, whereas flibanserin may work more like an antidepressant by correcting an imbalance of neurotransmitters in the brain to help restore sexual desire. It has effects on dopamine, norepinephrine, and serotonin levels in the brain.
Flibanserin comes as a tablet and is typically taken daily, at bedtime.
Common side effects of flibanserin include dizziness, nausea, and sleepiness. Flibanserin can also cause fainting, especially when used with alcohol.
You can buy Flibanserin from shop or buy Flibanserin online,In market,the puirty of Flibanserin is range from 60-98% purity,when considering buy Flibanserin powder online,the most important thing should care about is purity.
What Is Flibanserin ?
What is Flibanserin?Flibanserin is a drug developed to treat hypoactive sexual desire disorder (HSDD) in women. Women with HSDD have a chronic lack of interest in sex that cannot be explained by another medical condition. HSDD is also accompanied by feelings of distress.
Sometimes, flibanserin is called the “female Viagra,” but that term isn’t quite accurate. Viagra is a drug used to treat erectile dysfunction in men and works by improving blood flow to the penis. In other words, it mainly works on the genitals. Flibanserin is different because it works on a woman’s brain.
The brain is often considered a woman’s more important sexual organ. Much of her sexual response cycle originates in her brain.
Flibanserin works on three important brain chemicals: dopamine, norepinephrine, and serotonin. These chemicals are neurotransmitters. They are responsible for sending signals between the brain and other parts of the body through the nervous system.
Dopamine and norepinephrine are involved with sexual excitement. However, serotonin contributes to sexual inhibition and may dampen sex drive. It is thought that if these chemicals are out of balance – if dopamine and norepinephrine levels are too low and/or serotonin levels are too high – a woman might feel less sexual desire.Flibanserin works by raising levels of dopamine and norepinephrine while lowering levels of serotonin. In this way, chemicals that help promote sexual desire are increased and one that can suppress desire is decreased.
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What is Flibanserin powder?
Flibanserin raw powder,t,Bimt 17, Bimt-17-BS, Girosa; 2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperaziny l]ethyl]-;Flibanserin;Bimt17;3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one;Filbanserin;Flibanerins;1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one, is the material of Flibanserin,a kind of White crystalline powder,many steroids products supplier usually buy high purity Flibanserin powder online,make it into all kinds of brand finished Flibanserin,the detail of the Flibanserin as below:
Name: Flibanserin
CAS: 167933-07-5
Molecular Formula: C20H21F3N4O
Molecular Weight: 390.4
Melt Point: 225°C
Storage Temp.: RT
Color: White crystalline powder
Is Flibanserin powder a hormone?
Is Flibanserin is a hormore?No,doesn’t contain estrogen or testosterone or any other hormone. Flibanserinis a psychotropic medication. It acts specifically on serotonergic neurons in the brain, and has indirect effects on dopamine and norepinephrine.
Serotonin in the brain is generally thought to put the brakes on sex. Flibanserin may help ease up on the serotonin braking system, so libido can get going again.
What’s female HSDD?
HSDD,also called Female Hypoactive Sexual Desire.Female Hypoactive Sexual Desire Disorder (HSDD) is defined as a lack of desire for sex that leads to distress and interpersonal difficulties. HSDD is the most prevalent sexual disorder in women of all ages”Surgically post-menopausal women” at 20-49 years of age are at a greater risk of being diagnosed with HSDD, compared to those who are naturally post-menopausal, pre-menopausal, and surgically post-menopausal of advanced age.
you may got this HSDD When you have following Signs and Symptoms:
- Low sex drive
- Lack of sexual fantasies or thoughts
- Distress owing to low sex drive and an adverse effect on interpersonal relationships
HSDD could be caused by a multitude of factors including fatigue, lack of connection with the partner, hormonal changes due to pregnancy, childbirth, or menopause, illness, psychological issues, etc.
The signs and symptoms of Female Hypoactive Sexual Desire Disorder include a lack of sexual desires and sexual fantasies, and distress for such shortcomings
A diagnosis of Diminished Sex Drive in Women due to HSDD may involve physical, hormonal and psychological evaluations
The treatment is usually geared toward individual needs, because HSDD could potentially have many causative factors
A majority of women benefit from treatment of the underlying causes for Hypoactive Sexual Desire Disorder
What’s female HSDD treatment?
Sometimes just having a frank conversation with your partner can solve your HSDD. You also may choose to talk with your doctor, who may ask you about your relationship history and about past psychological issues related to your sexuality. Your doctor may also look for underlying medical conditions. You may ultimately be helped by:
Individual or couples sex therapy.
Treatment of an underlying medical condition.
Hormone therapy. Hormone balancing therapy for women and testosterone supplementation for some men with low testosterone levels can increase sexual desire.
Adding or changing medication. Sometimes the problem of HSDD can be solved simply by changing medications, from an older psychoactive drug that interferes with sexual desire, for example, to one of the newer drugs with fewer side effects. The addition of some drugs for underlying conditions — such as Levodopa used to treat Parkinson’s disease — has been found to help with male sexual desire, for example, by increasing production of the neurostransmitter dopamine.
Additionally, researchers are studying the safety and efficacy of a number of medical treatment options. These include a testosterone patch for women, which has proven particularly helpful after menopause or the surgical removal of ovaries — where much of a woman’s testosterone is produced. Two antidepressants, flibanserin and bupropion, are among the drugs being studied in the treatment of pre-menopausal women.
How Does Flibanserin powder Works?
Flibanserin is an oral drug used for treating low sexual desire in women,to treat hypoactive sexual desire disorder (HSDD) in women.Flibanserin works by raising levels of dopamine and norepinephrine while lowering levels of serotonin. In this way, chemicals that help promote sexual desire are increased and one that can suppress desire is decreased. Flibanserin affects the way the brain works by interfering with communication among the brain’s nerves in areas of the brain that control sexual desire and other pleasurable sensations. Nerves communicate with each other by making and releasing chemicals called neurotransmitters. The neurotransmitters travel to other nearby nerves where they attach to receptors on nerves. The attachment of neurotransmitters either stimulates or inhibits the function of the nearby nerves. Flibanserin blocks several of the receptors on nerves including dopamine type 4, and serotonin type 2A, 2B and 2C receptors. It also stimulates serotonin type 1A. How these effects improve sexual desire in women is unknown. Scientists think that flibanserin may regulate areas of the brain that control sexual desire in premenopausal women with reduced sexual interest and desire.
What’s Flibanserin powder mechanism of action?
The proposed Flibanserin powder mechanism of action involves regulation of several brain chemicals that may affect sexual desire, although the exact mechanism is not totally known. Flibanserin is a post-synaptic 5HT1A receptor agonist and 5HT2A receptor antagonist, as noted in FDA briefing documents, and has action in the central nervous system. The manufacturer states that flibanserin corrects an imbalance of dopamine and norepinephrine (both responsible for sexual excitement), while decreasing levels of serotonin (responsible for sexual satiety/inhibition). Flibanserin is not a hormonal drug and does not affect blood flow like the class of drugs approved for men with erectile dysfunction.
What’s the difference between Flibanserin and Sildenafil?(Addyi vs )
Different on apperance:
To dispense with the most obvious and superficial difference first, it’s important to note that Viagra, the first medication to treat erection problems in men, is blue in color, while Addyi is pink. It’s also another logical reason to select Viagra as our example since the other male impotence medications come in a variety of colors that would probably only confuse matters.
They Treat Different Forms of Sexual Dysfunction:
Addyi, the active ingredient of which is flibanserin, targets decreased sexual desire in women, while Viagra (sildenafil) is designed to make it easier for impotent men to get and keep an erection.
Although some men also suffer from a loss of libido, Viagra in no way helps to fan the flames of desire, which can be a purely psychological problem or stem from a combination of psychological and physiological factors. Counseling, antidepressants, and medications to increase a man’s testosterone levels may help to overcome such problems, but Viagra and the other male impotence drugs will do nothing to address them.
The Ways they work is different:
Viagra was the first of the so-called PDE5 inhibitors, is a drug used to treat erectile dysfunction in men and works by improving blood flow to the penis. In other words, it mainly works on the genitals. Flibanserin is different because it works on a woman’s brain.
The brain is often considered a woman’s more important sexual organ. Much of her sexual response cycle originates in her brain.Flibanserin works on three important brain chemicals: dopamine, norepinephrine, and serotonin. These chemicals are neurotransmitters. They are responsible for sending signals between the brain and other parts of the body through the nervous system.Flibanserin works by raising levels of dopamine and norepinephrine while lowering levels of serotonin. In this way, chemicals that help promote sexual desire are increased and one that can suppress desire is decreased.
Daily take or need take:
One very significant difference between flibanserin and Viagra and most of the other male impotence drugs is in how they are taken. To deliver optimal results, flibanserin should be taken daily. By contrast, Viagra and all but one of the other PDE5 inhibitors are taken on an as-needed basis, usually 30 minutes to an hour before sexual activity is expected to take place. The one exception among the male impotence drugs is Cialis for Daily Use, which is to be taken daily to allow men to achieve an erection whenever the need or desire arises.
Side Effects Differances:
The most common side effects reported by participants in clinical studies of flibanserin are drowsiness, particularly when combined with alcohol consumption, occasional fainting, and a decline in blood pressure.
Viagra also causes a temporary drop in blood pressure, which makes its use incompatible with nitrate-based drugs that do the same thing. However, the most common side effects of the little blue pill are back pain, flushing, headache, indigestion, muscular pain or tenderness, nasal congestion, and nausea, most of which tend to disappear upon continued use of the drug. More serious side effects of Viagra include a sudden loss of hearing or vision or an erection that lasts for more than four hours.
Is Flibanserin powder safe?
Is Flibanserin powder safe? I bet this might be a question that most people focus on. Let’a know it.Flibanserin is the first drug approved by the FDA for “hypoactive sexual desire disorder,”by the brand name Addyi, defined by the FDA as “characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to a co-existing medical or psychiatric condition, problems within the relationship, or the effects of a medication or other drug substance.”
Also The rapid post-licensure acquisition of Addyi’s manufacturer, Sprout Pharmaceuticals, by the Canadian company Valeant for $1 billion implies that Addyi is some sort of wonder drug — or, at least, that its hype is more about profit than helping women. And the evidence bears that out a bit.
Although it’s legal,safe, and in control,but sometimes need to be careful about the side effects.don’t overdose,and some other tips,we will talk later.
What is Flibanserin powder used for?
As what we said before,Flibanserin is used to treat women with hypoactive sexual desire disorder (HSDD; a low sexual desire that causes distress or interpersonal difficulty) who have not experienced menopause (change of life; the end of monthly menstrual periods). Flibanserin should not be used for the treatment of HSDD in women who have gone through menopause or in men or to improve sexual performance. Flibanserin is in a class of medications called a serotonin receptor 1A agonist/serotonin receptor 2A antagonist. It works by changing the activity of serotonin and other natural substances in the brain.
How should Flibanserin powder be used?
Flibanserin powder usually comes as a tablet to take by mouth. It is usually taken once daily at bedtime. Take flibanserin at bedtime every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take flibanserin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.If your symptoms do not improve after 8 weeks of treatment, call your doctor.
Before taking flibanserin powder
- tell your doctor and pharmacist if you are allergic to flibanserin, any other medications, or any of the ingredients in flibanserin tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: antidepressants such as fluoxetine (Prozac, Sarafem); antifungals; cimetidine (Tagamet); digoxin (Lanoxin); diphenhydramine (Benadryl); medications for anxiety or mental illness; medications for seizures such as carbamazepine (Epitol, Tegretol, Teril, others), phenobarbital, and phenytoin (Dilantin, Phenytek); opiate (narcotic) medications for pain control; oral contraceptives; proton pump inhibitors including dexlansoprazole (Dexilant), esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), or rabeprazole (Aciphex); ranitidine (Zantac); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); sedatives; sirolimus (Rapamune); sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially ginkgo, resveratrol, and St. Johns wort.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking flibanserin, call your doctor. Do not breast-feed while taking flibanserin.
- you should know that flibanserin may make you drowsy. Do not drive a car or operate machinery until at least 6 hours after your dose of flibanserin and until you know how this medication affects you.
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While taking Flibanserin powder
While you take Flibanserin,please pay attention to this:
- Flibanserin and Alcohol.Consuming alcohol while taking flibanserin can cause dangerous reactions.Avoid drinking alcohol while taking this medicine.
- Flibanserin and Grapefruit
- While you take Flibanserin,don’t take Grapefruit,or talk to your doctor before consuming grapefruit or grapefruit juice while taking flibanserin.The fruit might interact with how the drug works in your body.Flibanserin might make you dizzy or tired.
- Don’t drive or perform activities that require alertness until you know how this medicine affects you.Flibanserin may impair your thinking or reactions. Avoid driving or operating machinery for at least 6 hours after you take flibanserin, and until you know how this medicine will affect you. Dizziness or low blood pressure can cause falls or other accidents.
- Avoid taking an herbal supplement containing: ginkgo, resveratrol, or St. John’s wort.
- Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
After taking Flibanserin powder
After taking Flibanserin,it’s important to hopw how to store and dispose it,now let’s learn.
- Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
- Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community.
- It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.
What other drugs will affect flibanserin?
Taking this medicine with other drugs that make you sleepy or lower your blood pressure can worsen this effect. Ask your doctor before taking flibanserin with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Tell your doctor about all your current medicines and any you start or stop using, especially:
- cimetidine;
- gingko biloba;
- resveratrol; or
- St. John’s wort.
This list is not complete. Other drugs may interact with flibanserin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Dosage of Flibanserin
Recommend dosage of Flibanserin is 100 mg orally once per day at bedtime
Duration of therapy: This drug should be discontinued after 8 weeks if the patient does not report an improvement in symptoms.
Comments: This drug is not indicated to enhance sexual performance, and is not indicated for treatment in postmenopausal women or in men.
Use: Treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to a co-existing medical or psychiatric condition, problems within the relationship, or the effects of a medication or other drug substance.
Dose Adjustments
If Initiating this Drug Following Use of Moderate or Strong CYP450 3A4 Inhibitor:
-Start this drug 2 weeks after the last dose of the CYP450 3A4 inhibitor.
If Initiating a Moderate or Strong CYP450 3A4 Inhibitor Following Use of This Drug:
-Start the CYP450 3A4 inhibitor 2 days after the last dose of this drug.
Flibanserin Overdose
If you suspect an overdose, contact a poison control center or emergency room immediately.You can get in touch with a poison control center at 800-222-1222.
Missed Dose of Flibanserin
If you miss a dose of flibanserin, take your next dose at bedtime on the next day.
Don’t double up on doses or take extra medicine to make up for a missed dose.
Warning of Flibanserin
Contraindicated with moderate or strong CYP3A4 inhibitors
Coadministration with moderate or strong CYP3A4 inhibitors increases flibanserin concentrations, which can cause severe hypotension and syncope
Therefore, the use of moderate or strong CYP3A4 inhibitors is contraindicated
Contraindicated in patients with hepatic impairment
Contraindicated for use with any degree of hepatic impairment
Flibanserin exposure increased 4.5-fold in patients with hepatic impairment, compared with those with normal hepatic function, increasing the risk of hypotension, syncope, and CNS depression
What’s Side Effects of Flibanserin ?
Common Side Effects of Flibanserin
Tell your doctor if any of the following side effects become severe or don’t go away:
- Dizziness
- Nausea
- Sleepiness
- Insomnia
- Dry mouth
Serious Side Effects of Flibanserin
Tell your doctor right away if you experience any of the following serious side effects:
- Fainting or loss of consciousness
- Severe dizziness or sleepiness
- Signs of very low blood pressure (may include lightheadedness, nausea, clammy skin, blurry vision, depression, or dizziness)
Side effects and drug interactions with flibanserin should be well understood by both provider and patient. Addyi is contraindicated for use with alcohol, in patients with liver impairment, and in patients taking moderate-to-strong CYP3A4 inhibitors. Addyi is being approved with a risk evaluation and mitigation strategy (REMS), which includes elements to assure safe use (ETASU), as well as a Black Box Warning. Adverse effect data showed the most common side effects were dizziness, nausea and sleepiness. The risk of fainting, particularly when combined with alcohol, is a major concern. Due to this interaction Addyi will only be available from certified health care professionals and certified pharmacies. Health care professionals must assess the likelihood of the patient reliably abstaining from alcohol before prescribing Addyi and pharmacists must counsel on this interaction. The risk of fainting is also increased due to drug interactions with moderate or strong CYP3A4 inhibitors that interfere with the breakdown of Addyi in the body. FDA is requiring the manufacturer to conduct additional post-marketing studies to better define the interaction between flibanserin and alcohol.
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Author of this article:
Dr. Monique Hong graduated from UK Imperial College London Faculty of Medicine
Scientific Journal paper Author:
1.James A. Simon MD
IntimMedicine Specialists and George Washington University School of Medicine, Washington, DC, USA
2.Glen I. Spielmans PhD
Metropolitan State University, Department of Psychology, Saint Paul, MN, USA
3.S Goldfarb
Memorial Sloan Kettering Cancer Center
4.Noha M. Hosny
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Egypt
George Washington University School of Medicine and IntimMedicine Specialists
Stanford University School of Medicine, USA
In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. Aasraw has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge, acknowledge and commend the exhaustive research and development work done by the scientists working on this substance.