Product Description
Raw 17a Methyltestosterone Powder Basic Characters
Product Name: | 17-alpha-Methyltestosterone powder |
CAS number: | 58-18-4 |
Molecular Formula: | C20H30O2 |
Molecular Weight: | 302.45 |
Melt Point: | 162-168 °C |
Color: | White crystalline powder |
Storage Temp: | RT |
For the usage and dosage of 17α-methyltestosterone, please refer to the professional guidance provided by the original pharmaceutical company. As a professional manufacturer of 17α-methyltestosterone raw material powder, AASraw respects and appreciates the research contributions of the original pharmaceutical company and does not provide product usage recommendations.
What is 17α-Methyltestosterone?
17α-methyltestosterone (58-18-4), also called Methyltestosterone (MT or MET), is an oral anabolic steroid, which is synthesized for therapeutic purposes originally, such as low testosterone, anemia and delayed puberty in men, breast cancer treatment in women etc. As the derivative of testosterone, 17α-methyltestosterone has strong androgenic and anabolic effects and is often used in fitness and bodybuilding.
In addition, 17α-methyltestosterone is also widely used in aquaculture, especially for sex change of tilapia, improving fish production efficiency and profitability.
17α-Methyltestosterone for Medicial Use
① Testosterone replacement therapy (TRT)
As the androgen and anabolic steroid, 17α-Methyltestosterone (MT) can be used for testosterone replacement in men, especially testosterone deficiency or hypogonadism. And the typical dosage is 10 to 50 mg per day for men, which depends on testosterone deficiency and individual response. However, MT is not the first choice for TRT due to its potential hepatotoxicity and other side effects. Testosterone replacement therapy usually involves drugs such as Testosterone Enanthate or Testosterone Cypionate.
②Breast cancer treatment
In the United States, 17α-Methyltestosterone has been approved for women with advanced breast cancer who cannot undergo surgery. The common 17α-Methyltestosterone dosage is 10-20mg per day. But it can cause irreversible masculinization. With the development of medical technology, now there are newer and more targeted treatments for breast cancer. And the use of 17α-Methyltestosterone for breast cancer has become less common.
17α-Methyltestosterone for Bodybuilding
The anabolic effect of 17α-Methyltestosterone (MT) enables it to promote muscle growth and enhance performance like most steroids. And it can also enhance aggression, strength and concentration. In addition, 17α-Methyltestosterone has high oral bioavailability and is usually taken in tablets or pills. However, it is mainly metabolized by the liver, which exacerbates the side effects of liver poisoning.
17α-Methyltestosterone (MT) doesn’t have effectiveness due to the low ratio of anabolic metabolism and androgen. So bodybuilders usually stack it with other steroids such as Dianabol, Nandrolone, Trenbolone or Decanoate to enhance its effectiveness.
17α-Methyltestosterone for Sex Reversal in Fish
17α-Methyltestosterone (MET) has a methyl group attached to the 17th carbon position, which increases the oral bioavailability and stability of the steroid, making it effective in aquatic environments. Moreover, MET is a natural androgen. Therefore, it is now often used in aquaculture to promote fish growth and induce sex reversal in fish. It also has important practical significance in the production of monosexual populations of fish and improving growth rates.
17α-Methyltestosterone is often used for sex reversal in species such as tilapia and rainbow trout. In the case of tilapia, male fish grow faster and are larger than females. Therefore, in order to improve overall commercial production efficiency, 17α-Methyltestosterone will convert the sex of tilapia from genetic female to male, creating a monosexual male population. It also prevents fish from overbreeding.
In addition, 17α-Methyltestosterone is also used to promote fish growth and improve feed conversion. It can speed up the market size of fish and improve the profitability of fish farmers.
Fish farmers usually add 17α-methyltestosterone to fish feed or apply it through bath treatment so that it can be effectively absorbed. For tilapia, fish are most susceptible to the hormone at 1 to 3 weeks, ensuring effective sex reversal. And the typical 17α-methyltestosterone dosage is about 5 to 10 mg/kg feed. The 17α-methyltestosterone cycle length is usually continued for several weeks to ensure effective sex reversal.
However, this practice also has an impact on the environment. Residues of 17α-methyltestosterone may seep into natural water systems, affecting local aquatic ecosystems and wildlife. And people may also be concerned about the presence of hormone residues in the fish they eat, which may cause health hazards.
How does 17α-Methyltestosterone Work?
The mechanism action of 17α-Methyltestosterone (MT) likes most anabolic steroids, which mimicks the natural hormone testosterone. It binds to androgen receptors to promote protein synthesis, muscle growth, and various secondary male characteristics.
17α-Methyltestosterone Side Effects
Potential side effects are inevitable when 17α-methyltestosterone is used improperly or for a long time:
Common side effects of 17α-methyltestosterone include:
①Androgenic effects:
- Increased body hair
- Acne
- Oily skin
- Baldness
- Deepening of voice
- Increased aggression
- Seborrheic dermatitis
- Scalp hair loss
- Increased libido
②Estrogenic effects:
- Male breast development (male breast development)
- Water retention
③Hepatotoxicity
④Cardiovascular effects:
- Increased risk of heart disease
- Stroke
- Hypertension
⑤Other potential side effects may include:
- Headache
- Nausea
- Vomiting
- Insomnia
- Mood swings
It should be noted that these side effects may vary depending on personal factors, 17α-Methyltestosterone dosage, and duration of use. If you are considering using 17α-methyltestosterone, be sure to consult a healthcare professional in advance.
What are Differences between Testosterone and 17α-Methyltestosterone?
Testosterone is a natural hormone with a wide range of medical uses, essential for maintaining normal male sexual development and function. It is usually administered by injection. 17α-methyltestosterone is a synthetic variant for oral administration, modified to affect its metabolism but also increase the risk of side effects. Although they are used to control testosterone levels, testosterone is more popular among bodybuilders and 17α-methyltestosterone is more commonly used in aquaculture to help fish change sex.
Where to Buy 17α-Methyltestosterone Online?
The legal and health issues must be considered when looking to buy 17α-Methyltestosterone raw powder. It is available by prescription to treat specific conditions, such as testosterone deficiency or hormone replacement therapy in certain types of anemia. If you want to buy 17α-Methyltestosterone for other purposes, such as bodybuilding or fish transmutation, you can buy it on the store online or from reliable 17α-Methyltestosterone powder suppliers.
As the steroid powder professional supplier and manufacturer, AASraw can provide 17α-Methyltestosterone raw powder from small quantity to bulk order with competitive prices. And all of our steroid powder are manufactured under GMP conditions and undergo strict quality control system to meet the highest standards.
FAQ
①What is 17α-methyltestosterone half-life?
17α-methyltestosterone has a relatively short half-life, usually 4-6 hours. So 17α-methyltestosterone pills or tablets is required to take frequently to maintain blood levels.
②Is 17α-methyltestosterone legal?
17α-methyltestosterone is the controlled substance in many countries such as the United States, the European Union, etc. and is banned for use in competitive sports due to its anabolic properties. However, it is legal when prescribed by the healthcare professionals. Regardless, 17α-methyltestosterone is readily available from many steroid powder suppliers and online stores. AASraw is a professional 17α-methyltestosterone supplier and manufacturer, which welcomes inquiries and orders for 17α-methyltestosterone raw powder.
③How long does it take to see 17α-methyltestosterone results?
- If it is used to treat testosterone deficiency in men, some changes can be noticed within 2 to 4 weeks.
- If 17α-methyltestosterone is used to enhance athletic performance, bodybuilders can notice changes in muscle mass and strength within 1 to 3 weeks.
- If 17α-methyltestosterone is used in aquaculture, sex change can be observed in fish within 2 to 4 weeks, and fish growth can be observed within 4 to 8 weeks, especially for male fish.
4.Can 17α-methyltestosterone be detected in drug tests?
Yes, 17α-methyltestosterone can be detected in urine drug tests.
17 alpha Methyltestosterone Powder Testing Report-HNMR
What is HNMR and What does HNMR spectrum tell you? H Nuclear Magnetic Resonance (INMR)spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can(either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion.
17-Methyltestosterone powder( 58-18-4)-COA
17-Methyltestosterone powder( 58-18-4)-COA
How to buy 17 alpha Methyltestosterone Powder from AASraw?
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Author of this article:
Dr. Monique Hong graduated from UK Imperial College London Faculty of Medicine
Scientific Journal paper Author:
1.Robson Campos Silva
Laboratory of Cellular Biology, Department of Biological Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Alto da Jacuba, Diamantina, Minas Gerais, Brazil
2.Baadruzzoha Sarker
Department of Fish Biology and Genetics, Sylhet Agricultural University, Sylhet, Bangladesh
3.Rodrigo Zhouri Costa e Silva
Escola de Veterinária da Universidade Federal de Minas Gerais, Av. Antônio Carlos, n° 6627, Caixa Postal 567, Campus da UFMG, CEP 30123-970 Belo Horizonte, MG, Brazil
4.Somaye Alaedini
Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran
5.Thuchapol Karaket
Fisheries Science Program, Department of Agricultural Science, Faculty of Agriculture Natural Resources and Environment, Naresuan University, Phitsanulok, 65000, Thailand
In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. Aasraw has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge and commend the exhaustive research and development work done by the scientists working on this substance.
References
[1] “Steroid androgen 17 alpha Methyltestosteroneused in fish farming induces biochemical alterations in zebrafish adults”Carla Letícia Gediel Rivero-Wendt,Ana Luisa Miranda-VilelaORCID Icon,Inês Domingues,Rhaul Oliveira,Marta Sofia MonteiroORCID Icon,Monica A. M. Moura-MelloORCID Icon,Rosemary Matias,Amadeu Mortágua Velho Maia Soares &Cesar Koppe Grisolia. Pages 1321-1332 | Received 10 Mar 2020, Accepted 25 Jun 2020, Published online: 11 Jul 2020. https://doi.org/10.1080/10934529.2020.1790954
[2] Thuchapol Karaket, Aisawan Reungkhajorn, Pattareeya Ponza. “The optimum dose and period of 17α-Methyltestosterone immersion on masculinization of red tilapia (Oreochromis spp.)” Fisheries Science Program, Department of Agricultural Science, Faculty of Agriculture Natural Resources and Environment, Naresuan University, Phitsanulok, 65000, Thailand. https://doi.org/10.1016/j.aaf.2021.09.001
[3] “STUDY PROTOCOL FOR AN AQUACULTURE INVESTIGATIONAL NEW ANIMAL DRUG (INAD) EXEMPTION FOR THE USE OF 17-ALPHA Methyltestosterone IN TILAPIA (INAD #11-236)”
[4] Ahmed I. Mehrim, Fathy F. Khalil, Fayek H. Farrag and Mohamed M. Refaey. “17α-Methyltestosterone and Some Medicine Plants as Reproductive Controller Agents of Oreochromis niloticus” https://doi.org/10.1080/15222055.2012.758211
[5] M. Marjani, S. Jamili, P.G. Mostafavi, M. Ramin and A. Mashinchian, 2009. Influence of 17-Alpha Methyl Testosterone on Masculinization and Growth in Tilapia (Oreochromis mossambicus). Journal of Fisheries and Aquatic Science, 4: 71-74. DOI: 10.3923/jfas.2009.71.74 URL: https://scialert.net/abstract/?doi=jfas.2009.71.74
[6] Welder AA, Robertson JW, Melchert RB. “Toxic effects of anabolic-androgenic steroids in primary rat hepatic cell cultures.” J Pharmacol Toxicol Methods. 1995 Aug;33(4):187-95. doi: 10.1016/1056-8719(94)00073-d. PMID: 8527826
[7] Wang J, Zhou J, Yang Q, Wang W, Liu Q, Liu W, Liu S. Effects of 17 α-Methyltestosterone on the transcriptome, gonadal histology and sex steroid hormones in Pseudorasbora parva. Theriogenology. 2020 Oct 1;155:88-97. doi: 10.1016/j.theriogenology.2020.05.035. Epub 2020 Jun 23. PMID: 32645508
[8] El-Desoky el-SI, Reyad M, Afsah EM, Dawidar AA. Synthesis and chemical reactions of the steroidal hormone 17α-Methyltestosterone. Steroids. 2016 Jan;105:68-95. doi: 10.1016/j.steroids.2015.11.004. Epub 2015 Dec 2. PMID: 26639430
[9] Johnstone, R., D.J. Macintosh and R.S. Wright, 1983. Elimination of orally administered 17α-Methyltestosterone by Oreochromis mossambicus (tilapia) and Salmo gairdneri (rainbow trout) juveniles. Aquaculture, 35: 249-257.
[10] Special Issue:What hormones are typically used for fish sex reversal?
[11] What hormones are typically used for fish sex reversal(Authority)