Product Description
What is Selank?
Selank peptide is a synthetic peptide derived from tuftsin, a natural peptide found in the human body. It was developed in collaboration with the V.V.Zakusov Research Institute of Pharmacology at the Institute of Molecular Genetics, Russian Academy of Medical Sciences. In Russia, it has been approved for the treatment of generalized anxiety disorder (GAD) and is also used recreationally as a nootropic.
The specific sequence of the Selank peptide is Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). This sequence is designed to mimic the actions of tuftsin, which is involved in immune regulation and possesses anxiolytic properties. Selank has been extensively studied for its potential therapeutic effects, including improvements in anxiety and depression symptoms, enhancement of memory and cognition, and the promotion of a sense of calmness.[4][1]
The development of Selank aims to address the limitations of the natural tuftsin peptide, which has a short lifespan in the body. By synthesizing Selank, scientists seek to create a more stable and longer-lasting version of tuftsin, allowing for more effective and reliable therapeutic applications.
How does Selank work?
Selank exerts its effects on the body via a variety of methods.[6][1] While the precise mechanisms of action are unknown, here are some hypotheses about how Selank might work.
Neurotransmitter modulation: selank is thought to impact the concentration of monoamine neurotransmitters such as serotonin, dopamine, and norepinephrine. Selank may assist regulate mood, cognition, and emotional states by influencing the metabolism and levels of these neurotransmitters.
[5]0pt” data-window-control-info=”false”>Interaction with the immune system: selank is a synthetic tuftsin analog suggesting that it may have immunomodulatory properties. It is hypothesized to impact the balance of T helper cell cytokines and modulate the expression of Interleukin-6 (IL-6), both of which are important in immune response and regulation.
Influence on brain-derived neurotrophic factor (BDNF): selank has been demonstrated to boost BDNF expression in the hippocampus, a brain area critical for learning and memory.BDNF is essential for the growth, survival, and plasticity of neurons.
Enzyme inhibition: selank and its similar peptide medication Semax has been shown to inhibit enzymes involved in the breakdown of enkephalins and other endogenous regulatory peptides. This action may aid in the regulation of peptide levels and activity, which can affect pain perception and other physiological processes.
It is important to buy selank from a reputable supplier so that the quality of the peptide selank can be ensured. Professional selank manufacturer and supplier AASraw can supply selank with high quality for the support of the independent R&D center and factory. If you have needs,selank wholesale from AASraw is a great choice.
The benefits of Selank
Selank peptide has been studied for its potential therapeutic benefits and has shown various positive effects. Here are some potential benefits of Selank.
Anxiolytic effects
Selank has demonstrated anti-anxiety effects in clinical trials and animal studies. It may help reduce anxiety symptoms, improve the quality of life, and alleviate anxiety associated with different disorders.[5][2]
Cognitive enhancement
Selank has been found to enhance cognitive function and improve learning ability and memory. It may promote better attention, learning, and memory processes, potentially benefiting individuals with cognitive impairments or those looking to optimize their cognitive performance.
Mood regulation
Selank may have mood-regulating properties, potentially contributing to its anxiolytic effects. It has been studied for its ability to modulate the expression of brain-derived neurotrophic factor (BDNF), which plays a crucial role in mood regulation and the growth and maintenance of neurons.
Immune system modulation
Selank has been shown to have immunomodulatory effects, including stimulating the release of interferons and enhancing the production of T helper type 1 (Th1) cells. These effects may contribute to its potential immune-boosting properties.
Liver protection
Selank has exhibited antioxidant activity and has been shown to decrease levels of free radicals in the liver. It may also help restore the structure of liver cells, potentially contributing to liver health.
Before using selank, like with any peptide or therapeutic intervention, it is best to consult with a healthcare expert. They can offer advice, assess potential dangers, and track your progress to guarantee safe and proper use. Furthermore, buying peptides from the proper source is crucial.AASraw maintains stringent quality control and has created a batch of high-quality selank for sale. If necessary, you are welcome to buy peptide selank.
Selank vs Semax
Selank and Semax are both synthetic peptides that have been developed for their potential therapeutic effects. While they share some similarities, they also have distinct differences in their peptide sequences, derived sources, therapeutic uses, and administration methods. Here is a comparison between Selank and Semax:
· Peptide sequence
Selank: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
Semax: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
· Derived from
Selank:Selank is derived from tuftsin, a natural peptide involved in immune regulation and anxiolytic properties.
Semax:Semax is derived from an ACTH fragment, which is a peptide hormone involved in the regulation of cortisol production.
· Therapeutic uses
Selank: Selank has been approved in Russia for the treatment of generalized anxiety disorder (GAD). It is also used for depression, anhedonia (loss of pleasure), immune modulation, alcohol withdrawal symptoms, and cognitive enhancement.
Semax: Semax is primarily used for cognitive enhancement, including improving attention,memory, and cognitive functions. It has also been studied for neuroprotective effects and has potential applications in the treatment of stroke, traumatic brain injury, and eye diseases such as optic nerve neuropathy and glaucoma.
· Side effects
Selank: Rare and uncommon side effects associated with Selank may include dizziness, fatigue, hair loss, headaches, nasal irritations, nausea, and sore throat. However, these side effects are not commonly reported.
Semax: Semax is generally considered safe and well-tolerated, with rare and uncommon side effects reported.
· Cognitive effects
Selank: Selank has been studied for its potential to enhance cognition, memory, and learning abilities.
Semax: Semax is known for its cognitive-enhancing effects, particularly in improving attention, memory, and cognitive functions.
· Anxiolytic effects
Selank: Selank has shown anti-anxiety effects and is used for the treatment of anxiety disorders.
Semax: While Semax is primarily focused on cognitive enhancement, it may also have some anxiolytic effects, although it is not its primary therapeutic use.
· Neuroprotective effects
Selank: Selank has shown potential neuroprotective effects in studies.
Semax: Semax has been studied for its neuroprotective properties, particularly in the context of stroke and traumatic brain injury.
It is important to note that the information provided is a general overview, and the specific properties and uses of Selank and Semax may vary based on individual circumstances and regional availability. It is always advisable to consult with a healthcare professional for accurate and personalized information regarding these peptides.
Where to buy Selank?
There are various online retailers and vendors that specialize in selling peptides and related products. These online platforms may offer Selank for sale. It is important to ensure that you choose a reputable and reliable vendor when purchasing online.[3][4] Read customer reviews, check for certifications, and verify the authenticity and quality of the product.
AASraw is a reputable and professional manufacturer and supplier that specializes in providing a wide range of peptide raw powders and vials. With our expertise and experience in the industry, we offer high-quality products to meet the needs of researchers, pharmaceutical companies, and individuals involved in peptide synthesis and development. If you want to find a reliable Selank supplier, AASraw is a good choice.
Raw Selank Porder Testing Report-HNMR
What is HNMR and What does HNMR spectrum tell you? H Nuclear Magnetic Resonance (INMR)spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can(either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion.
How to buy Selank from AASraw?
❶To contact us by our email inquiry system, or leave your WhatsApp number to us, our customer service representative(CSR) will contact with you in 12 hours.
❷To provide us with your inquired quantity and address.
❸Our CSR will provide you with the quotation, payment term, tracking number, delivery ways, and estimated arrival date(ETA).
❹Payment done and the goods will be sent out in 12 hours.
❺Goods received and give comments.
Author of this article:
Dr. Monique Hong graduated from UK Imperial College London Faculty of Medicine
Scientific Journal paper Author:
1.Timur Kolomin
The Laboratory of Molecular Genetics of Hereditary Diseases,Department of Molecular Basis of Human Genetics,Institute of Molecular Genetics,Russian Academy of Sciences,Russia
2.T. Syunyakov
Department of Borderline Psychiatry,FSBI «Serbsky National Research Centre for Social and Forensic Psychiatry»,Moscow,Russia
3.T.N. Sollertinskaja
I.M.Sechenov Institute of Evolutionary Physiology and Biochemistry of RAS,Russia
4.Marina Morozova
The Department of Biomedical and Pharmaceutical Technology,Faculty of Biotechnology and Organic Synthesis,Lomonosov Moscow University of Fine Chemical Technology,Russia
In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. Aasraw has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge and commend the exhaustive research and development work done by the scientists working on this substance.
Reference
[1] Inozemtseva LS,Karpenko EA,Dolotov OV,Levitskaya NG,Kamensky AA,Andreeva LA,Grivennikov IA (2008).“Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo”. Doklady Biological Sciences. 421:241–243.
[2] SEMAX:a broad-spectrum drug effective stimulant of the nervous system. Institute of Molecular Genetics (in Russian).Moscow.Archived from the original on 2011-07-22.
[3] Solov’ev VB,Gengin MT,Sollertinskaia TN,Latynova IV,Zhivaeva LV (2012).“[Effect of selank on the main carboxypeptidases in the rat nervous tissue]”. Zhurnal Evoliutsionnoi Biokhimii I Fiziologii (in Russian). 48 (3):254–257.
[4] Uchakina ON,Uchakin PN,Miasoedov NF,Andreeva LA,Shcherbenko VE,Mezentseva MV,et al.(2008).“[Immunomodulatory effects of selank in patients with anxiety-asthenic disorders]”. Zhurnal Nevrologii I Psikhiatrii Imeni S.S.Korsakova. 108 (5):71–75.
[5] Kost NV,Sokolov OI,Gabaeva MV,Grivennikov IA,Andreeva LA,Miasoedov NF,Zozulia AA (2001).“Semax and selank inhibit the enkephalin-degrading enzymes from human serum”. Bioorganicheskaia Khimiia (in Russian). 27 (3):180–183.
[6] Semenova TP,Kozlovskiĭ II,Zakharova NM,Kozlovskaia MM (August 2010).“[Experimental optimization of learning and memory processes by selank]”. Eksperimental’naia i Klinicheskaia Farmakologiia. 73 (8):2–5.
