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Tadalafil powder (Copy)

Rating: SKU: 171596-29-5-1. Category:

Other names: Cialis powder, C351, Adcirca powder.

AASraw is the professional manufacturer of pure Tadalafil raw powder which has independent lab and large factory as support, all production will be carried out under CGMP regulation and trackable quality control system. The supply system is stable, both retail and wholesale orders are acceptable.Welcome to order from AASraw!

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Product Description

Tadalafil Video

Basic Characters

Name:Tadalafil powder
CAS:171596-29-5
Molecular Formula:C22H19N3O4
Molecular Weight:389.4
Melt Point:298-300°C
Storage Temp:20ºC
Color:White Powder

What is Tadalafil ?

Tadalafil Powder is a medication used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It is a phosphodiesterase type 5 (PDE5) inhibitor that works by relaxing the muscles in the blood vessels, allowing for increased blood flow to certain parts of the body. Tadalafil was first approved by the FDA in 2003 under the brand name Cialis and has since become a popular treatment option for men with ED. Tadalafil is also available as a generic medication, making it more accessible and affordable to those who need it. The Powder form of Tadalafil can be used for research purposes or for compounding medication. It is important to buy Tadalafil Powder with quality guarantee. Cialis is available in almost all of the local and online pharmacies but patients need to have a prescription to be able to buy it. The raw Tadalafil Powder don’t need the prescription. You can buy raw Tadalafil Powder from  AASRAW. Supplier AASRAW supplies high quality Tadalafil Powder with reasonable price.

How Tadalafil Powder works?

Tadalafil Powder is a phosphodiesterase type 5 (PDE5) inhibitor. In the case of erectile dysfunction (ED), Tadalafil Powder works by increasing blood flow to the penis, which can help a man achieve and maintain an erection during sexual activity. This effect is mediated by the relaxation of the smooth muscles in the blood vessels of the penis, which allows for increased blood flow to the area.

In the case of pulmonary arterial hypertension (PAH), Tadalafil Powder works by decreasing the blood pressure in the arteries that supply the lungs. This is achieved through the relaxation of the smooth muscles in the blood vessels of the lungs, which allows for increased blood flow and improved oxygenation.

It is important to note that Tadalafil Powder does not work without sexual stimulation. Sexual stimulation is necessary to initiate the release of nitric oxide (NO), which in turn stimulates the production of cGMP. Tadalafil Powder then works by inhibiting PDE5 and allowing for increased levels of cGMP to promote relaxation of the smooth muscles in the blood vessels.

Pharmaceutical uses of Tadalafil Powder

Tadalafil Powder can be used to make oral tablets or capsules for treating ED or PAH. It is also sometimes used in research studies.

· Treatment of erectile dysfunction (ED)

ED is a common condition in which a man has difficulty achieving or maintaining an erection during sexual activity. Tadalafil Powder works by inhibiting the enzyme PDE5, which is responsible for breaking down cGMP, a molecule that promotes relaxation of the smooth muscles in the penis and increases blood flow to the area. By inhibiting PDE5, Tadalafil Powder can increase cGMP levels and improve erectile function. Tadalafil Powder is often prescribed as a once-daily medication for the treatment of ED.

· Treatment of pulmonary arterial hypertension (PAH)

PAH is a rare condition in which the blood pressure in the arteries that supply the lungs is abnormally high. This can lead to shortness of breath, fatigue, and other symptoms. Tadalafil Powder is also a PDE5 inhibitor, and it works by relaxing the smooth muscles in the blood vessels of the lungs, which decreases the blood pressure in these vessels. This allows the heart to pump blood more effectively and improves the symptoms of PAH. Tadalafil Powder is usually administered as a once-daily medication for the treatment of PAH.

In addition to its primary uses, Tadalafil Powder has also been investigated for other potential therapeutic applications, such as the treatment of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) in men. However, these uses are not yet FDA-approved and more research is needed to fully understand their efficacy and safety.

Tadalafil Powder different forms of administration (oral tablets, capsules, injections, etc.)

Tadalafil Powder is typically available in the form of a crystalline white Powder, which is then formulated into various dosage forms for administration. The different forms of administration for Tadalafil Powder include:

Oral tablets: Tadalafil Powder can be formulated into oral tablets, which can be taken with or without food. The tablets are available in various dosages, including 2.5mg, 5mg, 10mg, and 20mg, and are taken as needed for the treatment of erectile dysfunction (ED), or as a once-daily medication for the treatment of pulmonary arterial hypertension (PAH).

Capsules: Tadalafil Powder can also be formulated into capsules, which are typically taken orally with or without food. Capsules may be easier to swallow than tablets for some patients, and may be available in different dosages depending on the intended use.

Sublingual tablets: Tadalafil Powder can be formulated into sublingual tablets, which are placed under the tongue and allowed to dissolve. This form of Tadalafil may have a faster onset of action compared to oral tablets, as the medication is absorbed directly into the bloodstream through the mucous membranes in the mouth.

Buccal film: Tadalafil Powder can also be formulated into a buccal film, which is placed inside the cheek and allowed to dissolve. This form of Tadalafil may also have a faster onset of action compared to oral tablets, as the medication is absorbed directly into the bloodstream through the mucous membranes in the mouth.

Injection: Tadalafil Powder can be formulated into an injectable form for the treatment of pulmonary arterial hypertension (PAH). This form of Tadalafil is administered by a healthcare professional via injection into a vein or under the skin.

It is important to note that different forms of Tadalafil may have different dosing and administration instructions, and patients should follow the instructions provided by their healthcare provider. Additionally, patients should inform their healthcare provider of any medications or supplements they are taking before starting treatment with Tadalafil Powder, as some medications may interact with Tadalafil Powder and increase the risk of side effects.

Dosage and administration of Tadalafil Powder

The dosage and administration of Tadalafil Powder will depend on the specific condition being treated, as well as individual patient factors such as age, weight, and medical history. It is important to follow the dosage and administration instructions provided by a healthcare provider even you buy raw Tadalafil Powder from reliable manufacturer, and to not exceed the recommended dose. The available dosages of Cialis (Tadalafil Powder) include 2.5, 5, 10, and 20 mg.

For the treatment of erectile dysfunction (ED), the typical starting dose of Tadalafil Powder is 10mg, taken orally as needed, prior to sexual activity. To increase the effectiveness of Cialis, later it can be corrected accordingly to reaction intensity and tolerance by decreasing it to 5 mg or raising it to 20 mg. Tadalafil Powder can be taken with or without food, but should be taken at approximately the same time each day to maintain consistent levels in the body. It is important to note that sexual stimulation is required for Tadalafil Powder to be effective.

For the treatment of pulmonary arterial hypertension (PAH), the typical starting dose of Tadalafil Powder is 40mg once daily, taken orally with or without food. The dose may be adjusted based on individual response and tolerance, and patients should be closely monitored for side effects.

Tadalafil Powder should be taken as directed by a healthcare provider, and patients should not take more than one dose in a 24-hour period even you buy raw Tadalafil Powder with AASRAW manufacturer, because the purity is at >99.9%. In the event of an overdose, patients should seek medical attention immediately.

It is important to note that Tadalafil Powder may interact with certain medications, including nitrates, alpha-blockers, and certain antibiotics and antifungal medications. Patients should inform their healthcare provider of all medications and supplements they are taking before starting treatment with Tadalafil Powder.

Have Realistic Expectations

Not every medication is effective for everyone. Tadalafil Powder is a widely effective drug, but this doesn’t mean it’s a slam-dunk perfect fit for you. According to the scientific literature, how quickly and effectively it works may vary.

For example, the medication can be useful for 24 to 36 hours after administration, and even up to 72 hours. So it could be effective for you for one entire day, while it could be effective for the next guy for three days.

Furthermore, one research discovered that 20mg of Tadalafil had a 52 percent effectiveness rate after 30 minutes, implying that some men could not have successful intercourse even a half hour after taking it.

One thing to keep in mind about Cialis’ effectiveness: it does not produce an instant and natural erection. Because PDE5 inhibitors do not directly affect the smooth muscles of the penis (but rather rely on the initial release of NO), sexual stimulation is still needed before your penis hardens.

What are the side effects of Tadalafil ?

As with any medication, it is important to be aware of potential side effects and precautions when taking Tadalafil Powder or Cialis.

(1)Side Effects of Tadalafil Powder:

Common side effects of Tadalafil Powder include:

Headache

Back pain

Muscle aches

Flushing

Indigestion

Runny or stuffy nose

Less common side effects may include:

Dizziness or lightheadedness

priapism, a painful erection lasting longer than 4 hours, which can cause tissue damage

low blood pressure

changes in hearing and vision

Chest pain or an irregular heartbeat

Shortness of breath or swelling in the hands, ankles, or feet

If you experience any of these side effects, it is important to contact your healthcare provider.

(2)Precautions When Taking Tadalafil Powder:

Avoid combining Tadalafil Powder with antihypertensive drugs, cannabis, large amounts of alcohol, fatty food, and products that contain grapefruit juice.

What else is important to know about taking Tadalafil Powder?

Age

Cialis may last longer in some individuals over the age of 65 because your body takes longer to process the medication. This influences how quickly it exits your body.

Cialis levels in your body can rise due to poor kidney function, raising side effects. In this situation, your doctor may adjust your dose.

Heart disease and other conditions

If you are over the age of 65, have a heart disease, or have liver or kidney problems, your doctor may need to adjust your Cialis dose and watch how the medication works for you.

Fake Cialis

Buy Cialis tablets only with a doctor’s prescription. PDE5 medications are among the most prevalent counterfeit medications distributed online. They can endanger one’s wellbeing. If you want to buy raw Tadalafil Powder bulk to produce tablets, always keep in mind to buy Tadalafil Powder from reliable supplier. Reliable supplier such as AASRAW will provide tested reports such as COA, HPLC and NMR

Take exactly as directed.

Cialis should be taken precisely as directed by your doctor. To prevent side effects, do not take extra doses or change your dosing schedule without first consulting your doctor.

Where to buy Tadalafil powder wholesale?

The FDA Trusted Source warns that some online pharmacies are not reputable providers. A person should always check Tadalafil reviews and recognize the signs of a reputable virtual pharmacy. Where to find the true and reliable Tadalafil Powder reviews and source? Maybe you can try to look through Reddit. Cialis is only available with a prescription. However, our Tadalafil Powder is the active ingredient of Cialis, you can find many Tadalafil Powder supplier online. There are many Tadalafil Powder for sale online, it is important to find the real and reliable supplier. AASRAW is the one manufacturer sell high quality Tadalafil Powder. Tadalafil Powder wholesale trades are much more common than retail sales as it is usually purchase in bulk directly from factory. Buy Tadalafil Powder Wholesale from AASRAW will get good price.

HNMR

Tadalafil powder HNMR

What is HNMR and What does HNMR spectrum tell you? 
H Nuclear Magnetic Resonance (INMR)spectroscopy is an analytical chemistry technique used in quality control
and research for determining the content and purity of a sample as well as its molecular structure. For 
example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR 
can(either be used to match against spectral libraries or to infer the basic structure directly. Once the
basic structure is known, NMR can be used to determine molecular conformation in solution as well as 
studying physical properties at the molecular level such as conformational exchange, phase changes,
solubility, and diffusion.

Tadalafil powder(171596-29-5)-COA

Tadalafil powder(171596-29-5)-COA

Janoshik test report

Noted: How to verify the test report from Janoshik?
① Go to Janoshik.com
② Click ‘Verify’
③ Enter task number and unique key which was showed on reports.

Tadalafil powder janoshik Test Report

How to buy  Tadalafil Powder from AASraw?

❶To contact us by our email inquiry system, or leave your WhatsApp number to us, our customer service representative(CSR) will contact with you in 12 hours.

❷To provide us your inquired quantity and address.

❸Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).

❹Payment done and the goods will be sent out in 12 hours.

❺Goods received and give comments.

Author of this article:
Dr. Monique Hong graduated from UK Imperial College London Faculty of Medicine

Scientific Journal paper Author:
1. Emanuel Fryk
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SU Sahlgrenska, 413 45 Gothenburg, Sweden
2. Dorota Rogacka
Department of Molecular Biotechnology, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, Gdansk 80-308, Poland
3. E. Deconinck
Scientific Direction Chemical and Physical Health Risks, Service of Medicines and Health Products, Sciensano, J. Wytsmanstraat 14, B-1050, Brussels, Belgium
4. Iman Shamohammadi
Department of Urology, Nemazee Hospital, Shiraz University of Medical Science, Shiraz, Iran
5. Natsumi Tomita
Department of Hospital Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe do-ri, Mizuho-ku, Nagoya 467-8603, Japan
In no way do these doctors or scientists endorse or advocate the purchase, sale, or use of this product for any reason. Aasraw has no affiliation or relationship, implied or otherwise, with these physicians. The purpose of citing them is to acknowledge and commend the exhaustive research and development work done by the scientists working on this substance.

Reference

[1] Mónica FZ, De Nucci G. “Tadalafil for the treatment of benign prostatic hyperplasia.”Expert Opin Pharmacother. 2019 Jun;20(8):929-937. doi: 10.1080/14656566.2019.1589452. Epub 2019 Mar 22. PMID: 30901259

[2] Sebastianelli A, Spatafora P, Morselli S, Vignozzi L, Serni S, McVary KT, Kaplan S, Gravas S, Chapple C, Gacci M. “Tadalafil Alone or in Combination with Tamsulosin for the Management for LUTS/BPH and ED.”Curr Urol Rep. 2020 Oct 27;21(12):56. doi: 10.1007/s11934-020-01009-7. PMID: 33108544

[3] Ruopp NF, Cockrill BA. “Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review.”JAMA. 2022 Apr 12;327(14):1379-1391. doi: 10.1001/jama.2022.4402. PMID: 35412560

[4] Sitbon O, Cottin V, Canuet M, Clerson P, Gressin V, Perchenet L, Bertoletti L, Bouvaist H, Picard F, Prévot G, Bergot E, Simonneau G. “Initial combination therapy of macitentan and tadalafil in pulmonary arterial hypertension.”Eur Respir J. 2020 Sep 3;56(3):2000673. doi: 10.1183/13993003.00673-2020. Print 2020 Sep. PMID: 32350101

[5] Prasetyo DT, Raharja PAR, Mantiri BJ, Ringoringo DRL, Rahman IA, Felizio J, Tambunan MP, Fadhly SF, Rahardjo HE. “Tadalafil Once a Day for Men with Erectile Dysfunction: Is It Superior than On-Demand Administration?”Acta Med Indones. 2019 Jul;51(3):275-281. PMID: 31699953

[6] Banjac NM, Vasović VM, Stilinović NP, Prodanović DV, Tomas Petrović AD, Vasović LV, Jakovljević VL. “Tadalafil in Increasing Doses: The Influence on Coronary Blood Flow and Oxidative Stress in Isolated Rat Hearts.”Pharmacology. 2022;107(3-4):150-159. doi: 10.1159/000520498. Epub 2021 Dec 10. PMID: 34903698


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